The potential of ARL4C and its-mediated genes in atherosclerosis and agent development

Foam cells are the risk factors for atherosclerosis. Recently, ARL4C, a member of the ADP-ribosylation factor family of GTP-binding proteins, was found to promote cholesterol efflux to decrease foam cell formation, suggesting that ARL4C may be a new promising target for the treatment of atherosclero...

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Bibliographic Details
Main Authors: Dan Liu, Jie Wang, Shuangshuang Zhang, Hongfei Jiang, Yudong Wu, Chao Wang, Wujun Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-03-01
Series:Frontiers in Pharmacology
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Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1513340/full
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