Effect of Early Continuous Veno-Venous Haemofiltration in Severe Acute Pancreatitis for the Prevention of Local Pancreatic Complications
Objective. To compare the conventional treatment and continuous veno-venous haemofiltration (CVVH) in severe acute pancreatitis (SAP) for the prevention of pseudocyst and walled-off necrosis. Patients and Methods. Forty-two patients were divided into two treatment groups: conventional treatment grou...
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| Format: | Article |
| Language: | English |
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Wiley
2022-01-01
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| Series: | Gastroenterology Research and Practice |
| Online Access: | http://dx.doi.org/10.1155/2022/7575231 |
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| author | Satish Chandra Yadav Bingqiang Zhang |
| author_facet | Satish Chandra Yadav Bingqiang Zhang |
| author_sort | Satish Chandra Yadav |
| collection | DOAJ |
| description | Objective. To compare the conventional treatment and continuous veno-venous haemofiltration (CVVH) in severe acute pancreatitis (SAP) for the prevention of pseudocyst and walled-off necrosis. Patients and Methods. Forty-two patients were divided into two treatment groups: conventional treatment group contained 24 patients and CVVH had 18. Conventional treatment group patients were treated symptomatically and according to the causes. CVVH group patients were treated symptomatically, and CVVH was done within 2 hours of admission. Results. In both groups, there was a decrease in amylase, lipase, CRP, IL-6, IL-10, TNF-alpha, Ranson score, Balthazar score, and APACHE-II score after 72 hours, but the decrease was significantly greater in CVVH patients. There were no any local pancreatic complications in CVVH patients, but 1 patient had an acute peripancreatic fluid collection, 2 patients had pseudocyst, and 2 patients had walled-off necrosis (WON), and a mortality one was seen in the conventional treatment group. Conclusion. The present study shows that early CVVH may be able to prevent the formation of pseudocyst and win in SAP patients. |
| format | Article |
| id | doaj-art-c8d487aa014f4413916dde4496eb65b3 |
| institution | Kabale University |
| issn | 1687-630X |
| language | English |
| publishDate | 2022-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Gastroenterology Research and Practice |
| spelling | doaj-art-c8d487aa014f4413916dde4496eb65b32025-02-03T06:10:55ZengWileyGastroenterology Research and Practice1687-630X2022-01-01202210.1155/2022/7575231Effect of Early Continuous Veno-Venous Haemofiltration in Severe Acute Pancreatitis for the Prevention of Local Pancreatic ComplicationsSatish Chandra Yadav0Bingqiang Zhang1The First Affiliated Hospital Chongqing Medical UniversityThe First Affiliated Hospital Chongqing Medical UniversityObjective. To compare the conventional treatment and continuous veno-venous haemofiltration (CVVH) in severe acute pancreatitis (SAP) for the prevention of pseudocyst and walled-off necrosis. Patients and Methods. Forty-two patients were divided into two treatment groups: conventional treatment group contained 24 patients and CVVH had 18. Conventional treatment group patients were treated symptomatically and according to the causes. CVVH group patients were treated symptomatically, and CVVH was done within 2 hours of admission. Results. In both groups, there was a decrease in amylase, lipase, CRP, IL-6, IL-10, TNF-alpha, Ranson score, Balthazar score, and APACHE-II score after 72 hours, but the decrease was significantly greater in CVVH patients. There were no any local pancreatic complications in CVVH patients, but 1 patient had an acute peripancreatic fluid collection, 2 patients had pseudocyst, and 2 patients had walled-off necrosis (WON), and a mortality one was seen in the conventional treatment group. Conclusion. The present study shows that early CVVH may be able to prevent the formation of pseudocyst and win in SAP patients.http://dx.doi.org/10.1155/2022/7575231 |
| spellingShingle | Satish Chandra Yadav Bingqiang Zhang Effect of Early Continuous Veno-Venous Haemofiltration in Severe Acute Pancreatitis for the Prevention of Local Pancreatic Complications Gastroenterology Research and Practice |
| title | Effect of Early Continuous Veno-Venous Haemofiltration in Severe Acute Pancreatitis for the Prevention of Local Pancreatic Complications |
| title_full | Effect of Early Continuous Veno-Venous Haemofiltration in Severe Acute Pancreatitis for the Prevention of Local Pancreatic Complications |
| title_fullStr | Effect of Early Continuous Veno-Venous Haemofiltration in Severe Acute Pancreatitis for the Prevention of Local Pancreatic Complications |
| title_full_unstemmed | Effect of Early Continuous Veno-Venous Haemofiltration in Severe Acute Pancreatitis for the Prevention of Local Pancreatic Complications |
| title_short | Effect of Early Continuous Veno-Venous Haemofiltration in Severe Acute Pancreatitis for the Prevention of Local Pancreatic Complications |
| title_sort | effect of early continuous veno venous haemofiltration in severe acute pancreatitis for the prevention of local pancreatic complications |
| url | http://dx.doi.org/10.1155/2022/7575231 |
| work_keys_str_mv | AT satishchandrayadav effectofearlycontinuousvenovenoushaemofiltrationinsevereacutepancreatitisforthepreventionoflocalpancreaticcomplications AT bingqiangzhang effectofearlycontinuousvenovenoushaemofiltrationinsevereacutepancreatitisforthepreventionoflocalpancreaticcomplications |