Optimal experimental design for parameter estimation of a cell signaling model.

Differential equation models that describe the dynamic changes of biochemical signaling states are important tools to understand cellular behavior. An essential task in building such representations is to infer the affinities, rate constants, and other parameters of a model from actual measurement d...

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Bibliographic Details
Main Authors: Samuel Bandara, Johannes P Schlöder, Roland Eils, Hans Georg Bock, Tobias Meyer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-11-01
Series:PLoS Computational Biology
Online Access:https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1000558&type=printable
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