Synthesis, Molecular Modeling, and Biological Activity of Zinc(II) Salts with 1,4-Bis(benzimidazol-2-yl)benzene
Zinc(II) halides and perchlorate react with 1,4-bis(benzimidazol-2-yl)benzene (L) in 1 : 2 molar ratio in n-butanol/2-methoxy ethanol (10 mL) at refluxing temperature to produce white/pale yellow-colored complexes of the formulae [ZnCl2L]H2O, [ZnBr2L]3H2O, and [Zn(OClO3)2L]HOCH2CH2CH2CH3. Zinc(II) i...
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| Format: | Article |
| Language: | English |
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Wiley
2013-01-01
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| Series: | Journal of Chemistry |
| Online Access: | http://dx.doi.org/10.1155/2013/265107 |
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| author | G. Krishnamurthy |
| author_facet | G. Krishnamurthy |
| author_sort | G. Krishnamurthy |
| collection | DOAJ |
| description | Zinc(II) halides and perchlorate react with 1,4-bis(benzimidazol-2-yl)benzene (L) in 1 : 2 molar ratio in n-butanol/2-methoxy ethanol (10 mL) at refluxing temperature to produce white/pale yellow-colored complexes of the formulae [ZnCl2L]H2O, [ZnBr2L]3H2O, and [Zn(OClO3)2L]HOCH2CH2CH2CH3. Zinc(II) iodide also reacts with L in 1 : 2 molar ratio in n-butanol (HOCH2CH2CH2CH3) to yield white-colored complex of the formula [ZnL2(OCH2CH2CH2CH3)2]. The complexes were characterized by elemental analysis, molar conductance measurements, thermal analysis, and IR, 1H-, 13C-NMR spectral studies. The complexes showed significant anthelmintic activity. The minimum energy configuration has been obtained for the zinc complexes using molecular modeling Pro Plus; a tool developed by ChemSW, inc, USA. |
| format | Article |
| id | doaj-art-c8bed9c9da8c4e1498c7bd4572ebc1e1 |
| institution | Kabale University |
| issn | 2090-9063 2090-9071 |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Chemistry |
| spelling | doaj-art-c8bed9c9da8c4e1498c7bd4572ebc1e12025-02-03T01:09:22ZengWileyJournal of Chemistry2090-90632090-90712013-01-01201310.1155/2013/265107265107Synthesis, Molecular Modeling, and Biological Activity of Zinc(II) Salts with 1,4-Bis(benzimidazol-2-yl)benzeneG. Krishnamurthy0Department of Chemistry, Sahyadri Science College (Autonomous), Kuvempu University, Shimoga-577203, Karnataka, IndiaZinc(II) halides and perchlorate react with 1,4-bis(benzimidazol-2-yl)benzene (L) in 1 : 2 molar ratio in n-butanol/2-methoxy ethanol (10 mL) at refluxing temperature to produce white/pale yellow-colored complexes of the formulae [ZnCl2L]H2O, [ZnBr2L]3H2O, and [Zn(OClO3)2L]HOCH2CH2CH2CH3. Zinc(II) iodide also reacts with L in 1 : 2 molar ratio in n-butanol (HOCH2CH2CH2CH3) to yield white-colored complex of the formula [ZnL2(OCH2CH2CH2CH3)2]. The complexes were characterized by elemental analysis, molar conductance measurements, thermal analysis, and IR, 1H-, 13C-NMR spectral studies. The complexes showed significant anthelmintic activity. The minimum energy configuration has been obtained for the zinc complexes using molecular modeling Pro Plus; a tool developed by ChemSW, inc, USA.http://dx.doi.org/10.1155/2013/265107 |
| spellingShingle | G. Krishnamurthy Synthesis, Molecular Modeling, and Biological Activity of Zinc(II) Salts with 1,4-Bis(benzimidazol-2-yl)benzene Journal of Chemistry |
| title | Synthesis, Molecular Modeling, and Biological Activity of Zinc(II) Salts with 1,4-Bis(benzimidazol-2-yl)benzene |
| title_full | Synthesis, Molecular Modeling, and Biological Activity of Zinc(II) Salts with 1,4-Bis(benzimidazol-2-yl)benzene |
| title_fullStr | Synthesis, Molecular Modeling, and Biological Activity of Zinc(II) Salts with 1,4-Bis(benzimidazol-2-yl)benzene |
| title_full_unstemmed | Synthesis, Molecular Modeling, and Biological Activity of Zinc(II) Salts with 1,4-Bis(benzimidazol-2-yl)benzene |
| title_short | Synthesis, Molecular Modeling, and Biological Activity of Zinc(II) Salts with 1,4-Bis(benzimidazol-2-yl)benzene |
| title_sort | synthesis molecular modeling and biological activity of zinc ii salts with 1 4 bis benzimidazol 2 yl benzene |
| url | http://dx.doi.org/10.1155/2013/265107 |
| work_keys_str_mv | AT gkrishnamurthy synthesismolecularmodelingandbiologicalactivityofzinciisaltswith14bisbenzimidazol2ylbenzene |