Cancer-associated fibroblasts, tumor and radiotherapy: interactions in the tumor micro-environment
Abstract Cancer-associated fibroblasts (CAFs) represent a group of genotypically non-malignant stromal cells in the tumor micro-environment (TME) of solid tumors that encompasses up to 80% of the tumor volume. Even though the phenotypic diversity and plasticity of CAFs complicates research, it is we...
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| Main Authors: | Kris T. P. M. Raaijmakers, Gosse J. Adema, Johan Bussink, Marleen Ansems |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2024-12-01
|
| Series: | Journal of Experimental & Clinical Cancer Research |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s13046-024-03251-0 |
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