A multi-antigen vaccinia vaccine broadly protected mice against SARS-CoV-2 and influenza A virus while also targeting SARS-CoV-1 and MERS-CoV

A multi-antigen vaccinia vaccine broadly protected mice against SARS-CoV-2 and influenza A virus while also targeting SARS-CoV-1 and MERS-CoV

IntroductionCoronaviruses and influenza viruses are significant respiratory pathogens that cause severe disease burdens and economic losses for society. Due to their diversity and evolution, vaccines typically require periodic updating to remain effective. An additional challenge is imposed by the p...

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Main Authors: Nan Gao, Tianhan Yang, Lanlan Dong, Wanda Tang, Kangli Cao, Longfei Ding, Cuisong Zhu, Shimeng Bai, Ai Xia, Youwei Zhu, Chen Zhao, Haoran Peng, Jianqing Xu, Xiaoyan Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-11-01
Series:Frontiers in Immunology
Subjects:
coronavirus
SARS-CoV-2
influenza virus
vaccinia virus Tiantan strain
multipathogen vaccine
mucosal immunity
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1473428/full
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https://www.frontiersin.org/articles/10.3389/fimmu.2024.1473428/full

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