FOXA1-dependent NSUN2 facilitates the advancement of prostate cancer by preserving TRIM28 mRNA stability in a m5C-dependent manner

Abstract RNA epigenetics is gaining increased attention for its role in the initiation, metastasis, and drug resistance of tumors. These studies have primarily focused on m6A modification. However, despite being the second most abundant modification found in RNA, the role of m5C modification in pros...

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Bibliographic Details
Main Authors: Zhenda Wang, Abudurexiti Mierxiati, Wenkai Zhu, Tian Li, Hua Xu, Fangning Wan, Dingwei Ye
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:npj Precision Oncology
Online Access:https://doi.org/10.1038/s41698-025-00904-x
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