MIC: A deep learning tool for assigning ions and waters in cryo-EM and crystal structures

Abstract At sufficiently high resolution, x-ray crystallography and cryogenic electron microscopy are capable of resolving small spherical map features corresponding to either water or ions. Correct classification of these sites provides crucial insight for understanding structure and function as we...

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Bibliographic Details
Main Authors: Laura Shub, Wenjin Liu, Georgios Skiniotis, Michael J. Keiser, Michael J. Robertson
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-61315-x
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