The role of senescence-related genes in major depressive disorder: insights from machine learning and single cell analysis

Abstract Background Evidence indicates that patients with Major Depressive Disorder (MDD) exhibit a senescence phenotype or an increased susceptibility to premature senescence. However, the relationship between senescence-related genes (SRGs) and MDD remains underexplored. Methods We analyzed 144 MD...

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Bibliographic Details
Main Authors: Kun Lian, Wei Yang, Jing Ye, Yilan Chen, Lei Zhang, Xiufeng Xu
Format: Article
Language:English
Published: BMC 2025-03-01
Series:BMC Psychiatry
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Online Access:https://doi.org/10.1186/s12888-025-06542-8
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