UW supplementation with AP39 improves liver viability following static cold storage

UW supplementation with AP39 improves liver viability following static cold storage

Abstract Static cold storage of donor livers at 4 °C incompletely arrests metabolism, ultimately leading to decreases in ATP levels, oxidative stress, cell death, and organ failure. Hydrogen Sulfide (H2S) is an endogenously produced gas, previously demonstrated to reduce oxidative stress, reduce ATP...

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Main Authors: McLean Taggart, Saige Holkup, Alexandra Tchir, Mohammadreza Mojoudi, Arnaud Lyon, Madeeha Hassan, Christopher Taveras, Ozge Sila Ozgur, James F. Markmann, Heidi Yeh, Korkut Uygun, Alban Longchamp
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-025-85302-w
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https://doi.org/10.1038/s41598-025-85302-w

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