Mesenchymal stem cells derived extracellular vesicles for chronic kidney disease: pleiotropic mechanisms of actions of a versatile therapy

Mesenchymal stem cells derived extracellular vesicles for chronic kidney disease: pleiotropic mechanisms of actions of a versatile therapy

Chronic kidney disease (CKD) has increasingly become a major health concern worldwide, globally affecting 10%–15% of adults, with significant implications for morbidity and mortality. This progressive condition can potentially evolve into end-stage renal disease (ESRD), requiring dialysis or renal t...

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Bibliographic Details
Main Authors: Elena Ceccotti, Marco Quaglia, Giovanni Camussi, Stefania Bruno
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
chronic renal damage
cell-free therapy
exosomes
fibrosis
murine models
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2025.1612193/full
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https://www.frontiersin.org/articles/10.3389/fbioe.2025.1612193/full

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