E46K α-Synuclein Mutation Fails to Promote Neurite Outgrowth by Not Inducing Cdc42EP2 Expression, Unlike Wild-Type or A53T α-Synuclein in SK-N-SH Cells

Background/Objectives: α-Synuclein (α-syn) protein is a major pathological agent of familial Parkinson’s disease (PD), and its levels and aggregations determine neurotoxicity in PD pathogenesis. Although the pathophysiological functions of α-syn have been extensively studied, its biological function...

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Bibliographic Details
Main Authors: Hyunja Jung, Seonghan Kim
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Brain Sciences
Subjects:
Online Access:https://www.mdpi.com/2076-3425/15/1/9
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