KIR and HLA-C interactions promote differential dendritic cell maturation and is a major determinant of graft failure following kidney transplantation.

KIR and HLA-C interactions promote differential dendritic cell maturation and is a major determinant of graft failure following kidney transplantation.

<h4>Background</h4>HLA-C is an important ligand for killer immunoglobulin like receptors (KIR) that regulate natural killer (NK) cell function. Based on KIR specificity HLA-C molecules are allocated into two groups, HLA-C1 or HLA-C2; HLA-C2 is more inhibiting to NK cell function than HLA...

Full description

Saved in:
Bibliographic Details
Main Authors: Raj Hanvesakul, Chandrashekhar Kubal, Jason Moore, Desley Neil, Mark Cook, Simon Ball, David Briggs, Paul Moss, Paul Cockwell
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0023631&type=printable
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items