Drimartol B, a sesquiterpene coumarin of the edible powder of Artemisia sphaerocephala seed, induced apoptosis in NSCLC cells via PI3K/AKT/FoxO3a pathway inhibition

Drimartol B, a sesquiterpene coumarin of the edible powder of Artemisia sphaerocephala seed, induced apoptosis in NSCLC cells via PI3K/AKT/FoxO3a pathway inhibition

In this study, Drimartol B, a sesquiterpene coumarin isolated from the edible powder of Artemisia sphaerocephala seeds, was investigated for its potential anti-NSCLC effects. Our findings showed that drimartol B inhibited the proliferation of both A549 and NCI-H1975 cells. Mechanistic studies reveal...

Full description

Saved in:
Bibliographic Details
Main Authors: Jiwen Li, Zhongyu Li, Mengru Cui, Mei Sun, Lei Men, Xiaojie Gong, Keke Li
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Journal of Functional Foods
Subjects:
Drimartol B
Non-small cell lung cancer
Apoptosis
Network pharmacology
Molecular docking
PI3K/AKT/FoxO3a
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464624006492
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

http://www.sciencedirect.com/science/article/pii/S1756464624006492

Similar Items