NIVO-TIL: combination anti-PD-1 therapy and adoptive T-cell transfer in untreated metastatic melanoma: an exploratory open-label phase I trial

NIVO-TIL: combination anti-PD-1 therapy and adoptive T-cell transfer in untreated metastatic melanoma: an exploratory open-label phase I trial

I the proliferation of intra-tumour CD8+ T cells is directly correlated with the clinical response, making tumour-infiltrating lymphocytes (TILs) a treatment of interest in combination with a PD-1 inhibitor, which is the undisputed gold standard in the management of metastatic melanoma. The aim of...

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Bibliographic Details
Main Authors: Jean-Matthieu L'Orphelin, Ugo Lancien, Jean-Michel Nguyen, Francisco J.S. Coronilla, Soraya Saiagh, Julie Cassecuel, Lise Boussemart, Anne Dompmartin, Brigitte Dréno
Format: Article
Language:English
Published: Medical Journals Sweden 2024-11-01
Series:Acta Oncologica
Subjects:
Immunotherapy
Immunotherapy Anti-PD-1
TILs
Adoptive cell transfer
melanoma
Online Access:https://medicaljournalssweden.se/actaoncologica/article/view/40495
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