Filiform fire needling therapy relieves T cells-mediated melanocyte apoptosis and dysfunction by inhibiting JAK/STAT3 pathway via Mfsd4a in vitiligo

Filiform fire needling therapy relieves T cells-mediated melanocyte apoptosis and dysfunction by inhibiting JAK/STAT3 pathway via Mfsd4a in vitiligo

Abstract We investigated the molecular mechanism of filiform fire needling therapy (FFN), an effective treatment option for vitiligo, focusing on its role in relieving depigmentation. Firstly, we validated the efficacy and safety of FFN in a study with 11 enrolled vitiligo patients. We then found th...

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Bibliographic Details
Main Authors: Yue Shi, Dong Chen, Yao Wang, Cong Zhang, Yana Cao, Yan Liu, Ting Song, Cheng Tan, Yongjun Peng
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Chinese Medicine
Subjects:
Filiform fire needling therapy
Vitiligo
Mfsd4a
Melanocytes
Melanin
Online Access:https://doi.org/10.1186/s13020-025-01172-4
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https://doi.org/10.1186/s13020-025-01172-4

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