Mechanisms for dysregulation of excitatory-inhibitory balance underlying allodynia in dorsal horn neural subcircuits.
Chronic pain is a wide-spread condition that is debilitating and expensive to manage, costing the United States alone around $600 billion in 2010. In a common symptom of chronic pain called allodynia, non-painful stimuli produce painful responses with highly variable presentations across individuals...
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Main Authors: | Alexander G Ginsberg, Scott F Lempka, Bo Duan, Victoria Booth, Jennifer Crodelle |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2025-01-01
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Series: | PLoS Computational Biology |
Online Access: | https://doi.org/10.1371/journal.pcbi.1012234 |
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