Attenuation of the plasma volume response to crystalloid fluid used for goal-directed fluid therapy

Abstract Background Goal-directed fluid therapy uses repeated bolus infusions of crystalloid or colloid fluid to increase the plasma volume for the purpose of challenging the patient’s position on the Frank-Starling curve. Each bolus is assumed to increase cardiac preload to the same degree. We exam...

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Bibliographic Details
Main Authors: Robert G. Hahn, Terry O’Brien
Format: Article
Language:English
Published: SpringerOpen 2025-06-01
Series:Annals of Intensive Care
Subjects:
Online Access:https://doi.org/10.1186/s13613-025-01495-3
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