Therapeutic impact of human trophoblast stem cells in peritoneal and pneumonia-induced sepsis in mice

Therapeutic impact of human trophoblast stem cells in peritoneal and pneumonia-induced sepsis in mice

Abstract Background Sepsis is a complex and life-threatening disease process related to a systemic response to severe infection. Due to the challenges of treating patients with sepsis, new therapies are being investigated, including cell-based approaches. Trophoblast stem cells (TSCs) are immune pri...

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Bibliographic Details
Main Authors: Narae Hwang, Gu Li, Ekaterina Murzin, Cassidy J. Mays, James A. Lederer, Xiaoli Liu, Mark A. Perrella
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Stem Cell Research & Therapy
Subjects:
Trophoblast stem cells
Sepsis
Acute organ injury
Inflammation
Bacterial clearance
Online Access:https://doi.org/10.1186/s13287-025-04479-z
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https://doi.org/10.1186/s13287-025-04479-z

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