GDF15-mediated enhancement of the Warburg effect sustains multiple myeloma growth via TGFβ signaling pathway
Abstract The Warburg effect, characterized by the shift toward aerobic glycolysis, is closely associated with the onset and advancement of tumors, including multiple myeloma (MM). Nevertheless, the specific regulatory mechanisms of glycolysis in MM and its functional role remain unclear. In this stu...
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Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2025-01-01
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Series: | Cancer & Metabolism |
Subjects: | |
Online Access: | https://doi.org/10.1186/s40170-025-00373-7 |
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