Hematologic and lymphatic disorders associated with chimeric antigen receptor T-cell therapy: a pharmacovigilance analysis of the FDA adverse event reporting system (FAERS) database

Hematologic and lymphatic disorders associated with chimeric antigen receptor T-cell therapy: a pharmacovigilance analysis of the FDA adverse event reporting system (FAERS) database

Abstract Background As the application of Chimeric Antigen Receptor T-cell (CAR-T) therapy in cancer treatment becomes increasingly widespread, associated hematologic and lymphatic system adverse events pose significant challenges to its clinical use. Therefore, we aim to comprehensively investigate...

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Bibliographic Details
Main Authors: Zhenpo Zhang, Jingping Zheng, Yankun Liang, Qimin Wu, Chufeng Ding, Lin Ma, Ling Su
Format: Article
Language:English
Published: BMC 2025-05-01
Series:BMC Cancer
Subjects:
CAR-T therapy
Hematologic and lymphatic system toxicity
Adverse events
FAERS
Online Access:https://doi.org/10.1186/s12885-025-14227-4
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https://doi.org/10.1186/s12885-025-14227-4

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