Concomitant Transverse Myelitis and Acute Axonal Sensory-Motor Neuropathy in an Elderly Patient
Diagnosing concomitant transverse myelitis (TM) and Guillain-Barré syndrome (GBS) can be challenging. We report a case of an elderly patient presenting with acute sensory and motor disturbances in the four limbs, associated with urinary retention, ophthalmoparesis, facial weakness, and dysarthria. E...
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| Language: | English |
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Wiley
2017-01-01
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| Series: | Case Reports in Immunology |
| Online Access: | http://dx.doi.org/10.1155/2017/7289474 |
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| author | L. M. Oliveira R. G. Cury L. H. Castro R. Nitrini |
| author_facet | L. M. Oliveira R. G. Cury L. H. Castro R. Nitrini |
| author_sort | L. M. Oliveira |
| collection | DOAJ |
| description | Diagnosing concomitant transverse myelitis (TM) and Guillain-Barré syndrome (GBS) can be challenging. We report a case of an elderly patient presenting with acute sensory and motor disturbances in the four limbs, associated with urinary retention, ophthalmoparesis, facial weakness, and dysarthria. Electrodiagnostic studies were consistent with acute motor sensory axonal neuropathy (AMSAN), and imaging showed a longitudinally extensive tumefactive contrast-enhancing hyperintense spinal cord lesion extending from T6 to the cone. Concomitant AMSAN and TM have not been previously reported in the elderly. Comorbid TM and other GBS variants have been previously reported. Intravenous methylprednisolone, plasma exchange, cyclophosphamide, or combination therapies are usually used, although there are no randomized controlled studies regarding treatment choices. |
| format | Article |
| id | doaj-art-c6dd369e348940f49a04c03e7afd2fda |
| institution | Kabale University |
| issn | 2090-6609 2090-6617 |
| language | English |
| publishDate | 2017-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Immunology |
| spelling | doaj-art-c6dd369e348940f49a04c03e7afd2fda2025-02-03T01:24:11ZengWileyCase Reports in Immunology2090-66092090-66172017-01-01201710.1155/2017/72894747289474Concomitant Transverse Myelitis and Acute Axonal Sensory-Motor Neuropathy in an Elderly PatientL. M. Oliveira0R. G. Cury1L. H. Castro2R. Nitrini3Department of Neurology, University of Sao Paulo, Sao Paulo, SP, BrazilDepartment of Neurology, University of Sao Paulo, Sao Paulo, SP, BrazilDepartment of Neurology, University of Sao Paulo, Sao Paulo, SP, BrazilDepartment of Neurology, University of Sao Paulo, Sao Paulo, SP, BrazilDiagnosing concomitant transverse myelitis (TM) and Guillain-Barré syndrome (GBS) can be challenging. We report a case of an elderly patient presenting with acute sensory and motor disturbances in the four limbs, associated with urinary retention, ophthalmoparesis, facial weakness, and dysarthria. Electrodiagnostic studies were consistent with acute motor sensory axonal neuropathy (AMSAN), and imaging showed a longitudinally extensive tumefactive contrast-enhancing hyperintense spinal cord lesion extending from T6 to the cone. Concomitant AMSAN and TM have not been previously reported in the elderly. Comorbid TM and other GBS variants have been previously reported. Intravenous methylprednisolone, plasma exchange, cyclophosphamide, or combination therapies are usually used, although there are no randomized controlled studies regarding treatment choices.http://dx.doi.org/10.1155/2017/7289474 |
| spellingShingle | L. M. Oliveira R. G. Cury L. H. Castro R. Nitrini Concomitant Transverse Myelitis and Acute Axonal Sensory-Motor Neuropathy in an Elderly Patient Case Reports in Immunology |
| title | Concomitant Transverse Myelitis and Acute Axonal Sensory-Motor Neuropathy in an Elderly Patient |
| title_full | Concomitant Transverse Myelitis and Acute Axonal Sensory-Motor Neuropathy in an Elderly Patient |
| title_fullStr | Concomitant Transverse Myelitis and Acute Axonal Sensory-Motor Neuropathy in an Elderly Patient |
| title_full_unstemmed | Concomitant Transverse Myelitis and Acute Axonal Sensory-Motor Neuropathy in an Elderly Patient |
| title_short | Concomitant Transverse Myelitis and Acute Axonal Sensory-Motor Neuropathy in an Elderly Patient |
| title_sort | concomitant transverse myelitis and acute axonal sensory motor neuropathy in an elderly patient |
| url | http://dx.doi.org/10.1155/2017/7289474 |
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