A pH-triggered self-releasing humic acid hydrogel loaded with porcine interferon α/γ achieves anti-pseudorabies virus effects by oral administration

Abstract Interferon α (IFNα) and interferon γ (IFNγ) play pivotal roles in mediating crucial biological functions, including antiviral activity and immune regulation. However, the efficacy of monomeric IFN is limited, and its administration relies solely on injection. To address this issue, we succe...

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Bibliographic Details
Main Authors: Maoyuan Sun, Yongli Shi, Baishi Lei, Wuchao Zhang, Jingjing Feng, Shenghu Ge, Wanzhe Yuan, Kuan Zhao
Format: Article
Language:English
Published: BMC 2024-11-01
Series:Veterinary Research
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Online Access:https://doi.org/10.1186/s13567-024-01411-w
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