Microtubules regulate migratory polarity through Rho/ROCK signaling in T cells.

Microtubules regulate migratory polarity through Rho/ROCK signaling in T cells.

<h4>Background</h4>Migrating leukocytes normally have a polarized morphology with an actin-rich lamellipodium at the front and a uropod at the rear. Microtubules (MTs) are required for persistent migration and chemotaxis, but how they affect cell polarity is not known.<h4>Methodolo...

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Bibliographic Details
Main Authors: Aya Takesono, Sarah J Heasman, Beata Wojciak-Stothard, Ritu Garg, Anne J Ridley
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0008774&type=printable
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