Chromatin state origins of uterine leiomyoma

Abstract Aberrations in the regulatory genome play a pivotal role in population-level disease predisposition. Annotation of the regulatory regions using appropriate primary tissues - instead of cell lines affected by selection and other confounding factors - could shed new light into mechanisms unde...

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Main Authors: Maritta Räisänen, Eevi Kaasinen, Maija Jäntti, Aurora Taira, Emma Siili, Ralf Bützow, Oskari Heikinheimo, Annukka Pasanen, Auli Karhu, FinnGen, Davide G. Berta, Niko Välimäki, Lauri A. Aaltonen
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-59646-w
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