Controversies in the Management of Endometrial Cancer
Endometrial cancer (EC) remains the most common malignancy of the female genital tract. The median age at diagnosis is the sixth decade, with abnormal uterine bleeding at the presentation in 90% of the patients. Surgical treatment, including complete hysterectomy, removal of remaining adnexal struct...
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Format: | Article |
Language: | English |
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Wiley
2010-01-01
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Series: | Obstetrics and Gynecology International |
Online Access: | http://dx.doi.org/10.1155/2010/638165 |
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author | V. Masciullo G. Amadio D. Lo Russo I. Raimondo A. Giordano G. Scambia |
author_facet | V. Masciullo G. Amadio D. Lo Russo I. Raimondo A. Giordano G. Scambia |
author_sort | V. Masciullo |
collection | DOAJ |
description | Endometrial cancer (EC) remains the most common malignancy of the female genital tract. The median age at diagnosis is the sixth decade, with abnormal uterine bleeding at the presentation in 90% of the patients. Surgical treatment, including complete hysterectomy, removal of remaining adnexal structures, and an appropriate surgical staging, represents the milestone of curative therapy for patients with EC. Adjuvant therapy is necessary in patients at high risk of recurrence. Conservative treatment approaches should be used in selected cases for women with a desire of fertility preservation. This review summarizes the management of EC and discusses current controversies regarding the role of lymphadenectomy and radiotherapy in patients with intermediate-risk tumors confined to the uterus. |
format | Article |
id | doaj-art-c6b715ea10984bdcb3dbdb4cfdae94c1 |
institution | Kabale University |
issn | 1687-9589 1687-9597 |
language | English |
publishDate | 2010-01-01 |
publisher | Wiley |
record_format | Article |
series | Obstetrics and Gynecology International |
spelling | doaj-art-c6b715ea10984bdcb3dbdb4cfdae94c12025-02-03T01:10:32ZengWileyObstetrics and Gynecology International1687-95891687-95972010-01-01201010.1155/2010/638165638165Controversies in the Management of Endometrial CancerV. Masciullo0G. Amadio1D. Lo Russo2I. Raimondo3A. Giordano4G. Scambia5Division of Gynecologic Oncology, Catholic University of Sacred Heart, 00168 Rome, ItalyDivision of Gynecologic Oncology, Catholic University of Sacred Heart, 00168 Rome, ItalyDivision of Gynecologic Oncology, Catholic University of Sacred Heart, 00168 Rome, ItalyDivision of Gynecologic Oncology, Catholic University of Sacred Heart, 00168 Rome, ItalyCenter for Biotechnology, College of Science and Technology, Temple University, Philadelphia, PA 19122, USADivision of Gynecologic Oncology, Catholic University of Sacred Heart, 00168 Rome, ItalyEndometrial cancer (EC) remains the most common malignancy of the female genital tract. The median age at diagnosis is the sixth decade, with abnormal uterine bleeding at the presentation in 90% of the patients. Surgical treatment, including complete hysterectomy, removal of remaining adnexal structures, and an appropriate surgical staging, represents the milestone of curative therapy for patients with EC. Adjuvant therapy is necessary in patients at high risk of recurrence. Conservative treatment approaches should be used in selected cases for women with a desire of fertility preservation. This review summarizes the management of EC and discusses current controversies regarding the role of lymphadenectomy and radiotherapy in patients with intermediate-risk tumors confined to the uterus.http://dx.doi.org/10.1155/2010/638165 |
spellingShingle | V. Masciullo G. Amadio D. Lo Russo I. Raimondo A. Giordano G. Scambia Controversies in the Management of Endometrial Cancer Obstetrics and Gynecology International |
title | Controversies in the Management of Endometrial Cancer |
title_full | Controversies in the Management of Endometrial Cancer |
title_fullStr | Controversies in the Management of Endometrial Cancer |
title_full_unstemmed | Controversies in the Management of Endometrial Cancer |
title_short | Controversies in the Management of Endometrial Cancer |
title_sort | controversies in the management of endometrial cancer |
url | http://dx.doi.org/10.1155/2010/638165 |
work_keys_str_mv | AT vmasciullo controversiesinthemanagementofendometrialcancer AT gamadio controversiesinthemanagementofendometrialcancer AT dlorusso controversiesinthemanagementofendometrialcancer AT iraimondo controversiesinthemanagementofendometrialcancer AT agiordano controversiesinthemanagementofendometrialcancer AT gscambia controversiesinthemanagementofendometrialcancer |