Epitranscriptomic analysis reveals clinical and molecular signatures in glioblastoma

Epitranscriptomic analysis reveals clinical and molecular signatures in glioblastoma

Abstract This study characterizes the glioblastoma (GB) epitranscriptomic landscape in patient who evolve to progressive disease (PD) or pseudo-progressive disease (psPD). Novel differences in N6-Methyladenosine (m6A) RNA methylation patterns between these groups are identified in the first biopsy....

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Bibliographic Details
Main Authors: Glaucia Maria de Mendonça Fernandes, Wesley Wang, Saman Seyed Ahmadian, Daniel Jones, Jing Peng, Pierre Giglio, Monica Venere, José Javier Otero
Format: Article
Language:English
Published: BMC 2025-04-01
Series:Acta Neuropathologica Communications
Subjects:
Glioblastoma
Progression disease
Pseudo-progression
Novel enhancement
Epitranscriptome
Online Access:https://doi.org/10.1186/s40478-025-01966-5
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