BHLHE41 Overexpression Alleviates the Malignant Behavior of Colon Cancer Cells Induced by Hypoxia via Modulating HIF-1α/EMT Pathway

Objective. BHLHE41 has been shown to be a marker of tumorigenesis. Colon cancer (CC) is a common malignant tumor of colonic mucosa. This study mainly explored the mechanism of BHLHE41 in alleviating malignant behavior of hypoxia-induced CC cells. Methods. The levels of BHLHE41 in CC and normal cell...

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Bibliographic Details
Main Authors: Sheng Chen, Quan-Jin Dong, Zi-Ang Wan, Shan Gao, Shi-Liang Tu, Rui Chai
Format: Article
Language:English
Published: Wiley 2022-01-01
Series:Gastroenterology Research and Practice
Online Access:http://dx.doi.org/10.1155/2022/6972331
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