Chemosensitization and Molecular Docking Assessment of Dio-NPs on Resistant Breast Cancer Cells to Tamoxifen

Chemosensitization and Molecular Docking Assessment of Dio-NPs on Resistant Breast Cancer Cells to Tamoxifen

<b>Background:</b> Diosgenin, a powerful compound found in fenugreek and <i>Dioscorea villosa</i>, has diverse pharmacological effects. This study examines the anticancer potential of diosgenin nanoparticles (Dio-NPs) against DMBA-induced breast cancer in mice in combination...

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Bibliographic Details
Main Authors: Amr A. Abd-Elghany, Ebtesam A. Mohamad, Abdullah Alqarni, Mohammed A. Hussein, Mohamed S. Mansour
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Pharmaceuticals
Subjects:
diosgenin
tamoxifen
breast cancer
Dio-NPs
CDKs
Akt proteins
Online Access:https://www.mdpi.com/1424-8247/18/4/452
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