Biosynthesized nanoparticles of Tibetan medicine mercuric sulfide preparation to promote endocytosis and realize drug crossing through blood brain barrier

Biosynthesized nanoparticles of Tibetan medicine mercuric sulfide preparation to promote endocytosis and realize drug crossing through blood brain barrier

Abstract β-HgS as the main component of Tibetan medicine Zuotai (ZT) is widely used in the treatment of central nervous system diseases. Although the synergism of HgS has been clinically verified for more than 2000 years, its synergetic mechanism is still an unsolved mystery and a huge challenge. No...

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Bibliographic Details
Main Authors: Wenjing Jia, Huilan Yue, Liying Liu, Luya Wang, Lin Zhang, Jihong Tao, Guoying Zhou, Lixin Wei, Hongxin Dong, Rinchen Dhondrup, Xiaohui Zhao
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Journal of Nanobiotechnology
Subjects:
Zuotai
Tibetan medicine
Biosynthesis
Protein corona
Endocytosis
HgS
Online Access:https://doi.org/10.1186/s12951-025-03525-5
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https://doi.org/10.1186/s12951-025-03525-5

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