Human mitochondrial leucyl tRNA synthetase can suppress non cognate pathogenic mt‐tRNA mutations
Abstract Disorders of the mitochondrial genome cause a wide spectrum of disease, these present mainly as neurological and/or muscle related pathologies. Due to the intractability of the human mitochondrial genome there are currently no effective treatments for these disorders. The majority of the pa...
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| Main Authors: | Hue Tran Hornig‐Do, Arianna Montanari, Agata Rozanska, Helen A Tuppen, Abdulraheem A Almalki, Dyg P Abg‐Kamaludin, Laura Frontali, Silvia Francisci, Robert N Lightowlers, Zofia M Chrzanowska‐Lightowlers |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Springer Nature
2014-01-01
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| Series: | EMBO Molecular Medicine |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/emmm.201303202 |
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