Serum assisted PD-L1 aptamer screening for improving its stability

Abstract Aptamers have shown potential for diagnosing clinical markers and targeted treatment of diseases. However, their limited stability and short half-life hinder their broader applications. Here, a real sample assisted capture-SELEX strategy is proposed to enhance the aptamer stability, using t...

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Bibliographic Details
Main Authors: Yu Zhou, Haozhe Zhang, Yujing Ding, Changyuan Yu, Hao Li
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Scientific Reports
Subjects:
Online Access:https://doi.org/10.1038/s41598-025-85813-6
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