Prognostic Impact of Oncogenic Fibroblast Growth Factor Receptor Alterations in Patients With Advanced Solid Tumors in a Real‐World Setting

Prognostic Impact of Oncogenic Fibroblast Growth Factor Receptor Alterations in Patients With Advanced Solid Tumors in a Real‐World Setting

ABSTRACT Background Somatic FGFR gene alterations (FGFRalt) may act as oncogenic drivers across several cancers. The prognostic impact of FGFRalt in solid tumors is not fully understood. We assessed the prognostic impact of FGFRalt on overall survival (OS) in a tumor‐agnostic real‐world cohort of pa...

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Main Authors: Levon Demirdjian, Spyros Triantos, Kristopher Standish, Shibu Thomas, Qi Xia, Jiarui Zhang, Joel Greshock, Julie Paone, Paige Sheridan, Shubham Pant, Christophe Massard, David A. Reardon, Yohann Loriot, Martin Schuler, Hussein Sweiti
Format: Article
Language:English
Published: Wiley 2025-02-01
Series:Cancer Medicine
Subjects:
erdafitinib
fibroblast growth factor inhibitor
real‐world evidence
tumor agnostic
Online Access:https://doi.org/10.1002/cam4.70546
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https://doi.org/10.1002/cam4.70546

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