Increased DNA Copy Number Variation Mosaicism in Elderly Human Brain
Aging is a complex process strongly determined by genetics. Previous reports have shown that the genome of neuronal cells displays somatic genomic mosaicism including DNA copy number variations (CNVs). CNVs represent a significant source of genetic variation in the human genome and have been implica...
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Main Authors: | Darine Villela, Claudia K. Suemoto, Renata Leite, Carlos Augusto Pasqualucci, Lea T. Grinberg, Peter Pearson, Carla Rosenberg |
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Format: | Article |
Language: | English |
Published: |
Wiley
2018-01-01
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Series: | Neural Plasticity |
Online Access: | http://dx.doi.org/10.1155/2018/2406170 |
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