Novel kinase-activating genetic events in non-small cell lung carcinomas

Novel kinase-activating genetic events in non-small cell lung carcinomas

Aim: This study aimed at the identification of new druggable alterations in non-small cell lung carcinomas (NSCLCs). Methods: RNA next generation sequencing (NGS) analysis for 650 protein kinase genes was performed for 89 NSCLCs obtained from young-onset and/or female non-smokers, who were negative...

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Main Authors: Elena V. Preobrazhenskaya, Rimma S. Mulkidjan, Fyodor A. Zagrebin, Alexandr A. Romanko, Evgeniya S. Saitova, Polina R. Korzun, Jeyla O. Binnatova, Vladislav I. Tiurin, Ilya V. Bizin, Evgeny N. Imyanitov
Format: Article
Language:English
Published: Open Exploration Publishing Inc. 2025-07-01
Series:Exploration of Targeted Anti-tumor Therapy
Subjects:
lung cancer
kinases
fusion
mutation
expression
rna
next generation sequencing (ngs)
Online Access:https://www.explorationpub.com/uploads/Article/A1002330/1002330.pdf
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