Inflammatory biomarkers and therapeutic potential of milk exosome-mediated CCL7 siRNA in murine intestinal ischemia-reperfusion injury

Inflammatory biomarkers and therapeutic potential of milk exosome-mediated CCL7 siRNA in murine intestinal ischemia-reperfusion injury

BackgroundIntestinal ischemia-reperfusion injury (IIRI) is a severe clinical condition associated with high morbidity and mortality. Despite advances in understanding the pathophysiology of IIRI, effective diagnostic and therapeutic strategies remain limited.MethodsUsing transcriptome sequencing in...

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Bibliographic Details
Main Authors: WenDong Chen, WenPing Xu, Li Ma, Chun Bi, MeiXu Yang, Wei Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Immunology
Subjects:
intestinal ischemia-reperfusion injury
biomarkers
inflammation
CCL7
milk-derived exosomes
siRNA delivery
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1513196/full
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