Agapanthussaponin A from the Underground Parts of <i>Agapanthus africanus</i> Induces Apoptosis and Ferroptosis in Human Small-Cell Lung Cancer Cells

Agapanthussaponin A from the Underground Parts of <i>Agapanthus africanus</i> Induces Apoptosis and Ferroptosis in Human Small-Cell Lung Cancer Cells

To explore the potential seed compounds from natural products as anticancer agents against small-cell lung cancer (SCLC), the underground parts of <i>Agapanthus africanus</i>, a plant commonly used for ornamental purposes, were investigated. Three spirostan-type steroidal glycosides (<...

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Bibliographic Details
Main Authors: Tomoki Iguchi, Tamami Shimazaki, Yoshihiro Mimaki
Format: Article
Language:English
Published: MDPI AG 2025-07-01
Series:Molecules
Subjects:
<i>Agapanthus africanus</i>
agapanthussaponin A
SBC-3 cell
apoptosis
ferroptosis
steroidal glycoside
Online Access:https://www.mdpi.com/1420-3049/30/15/3189
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