Unraveling the mechanisms of irAEs in endometrial cancer immunotherapy: insights from FAERS and scRNA-seq data

Unraveling the mechanisms of irAEs in endometrial cancer immunotherapy: insights from FAERS and scRNA-seq data

Abstract Endometrial cancer (EC) is one of the most common malignancies in women. In recent years, immunotherapy has gradually become a significant treatment option. However, the mechanisms underlying immune checkpoint inhibitor (ICI)-related Adverse Events (AEs) remain poorly understood, posing sig...

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Bibliographic Details
Main Authors: Lu Zhang, Mengjie Yang, Yiqian Zhang, Jianfa Lan, Qionghua Chen
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Scientific Reports
Subjects:
Endometrial cancer
Immunotherapy
PD-1 inhibitors
Adverse events
Single-cell analysis
FAERS database
Online Access:https://doi.org/10.1038/s41598-025-02723-3
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https://doi.org/10.1038/s41598-025-02723-3

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