CD47 is required for mesenchymal progenitor proliferation and fracture repair
Abstract CD47 is a ubiquitous and pleiotropic cell-surface receptor. Disrupting CD47 enhances injury repair in various tissues but the role of CD47 has not been studied in bone injuries. In a murine closed-fracture model, CD47-null mice showed decreased callus bone formation as assessed by microcomp...
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| Main Authors: | Robert L. Zondervan, Christina A. Capobianco, Daniel C. Jenkins, John D. Reicha, Livia Fredrick, Charles Lam, Jeanna T. Schmanski, Jeffery S. Isenberg, Jaimo Ahn, Ralph S. Marcucio, Kurt D. Hankenson |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2025-03-01
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| Series: | Bone Research |
| Online Access: | https://doi.org/10.1038/s41413-025-00409-0 |
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