Network analysis and experimental validation to investigate chenpi against functional dyspepsia through TLR4/MyD88 by regulating the gut microbial structure

Network analysis and experimental validation to investigate chenpi against functional dyspepsia through TLR4/MyD88 by regulating the gut microbial structure

Functional dyspepsia (FD) is a prevalent functional gastrointestinal disorder characterized by the absence of organic lesions; it affects nearly one-fifth of the global population. There is currently no specific drug for treating it. Citri reticulatae Pericarpium (CRP) has been utilized in China for...

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Bibliographic Details
Main Authors: Jinfang Hu, Xu Wang, Xiaoqiu Guo, Wen Wen, Jin Xue, Zhengzheng Liao, Lihua Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-02-01
Series:Frontiers in Pharmacology
Subjects:
functional dyspepsia
Citri Reticulatae Pericarpium
inflammation
TLR4/MyD88
gut microbe
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1495799/full
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https://www.frontiersin.org/articles/10.3389/fphar.2025.1495799/full

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