A combined adjuvant and ferritin nanocage based mucosal vaccine against Streptococcus pneumoniae induces protective immune responses in a murine model

Abstract Protein nanocages are multimeric structures that can be engineered to mimic the molecular conformation of microorganisms. Based on previous findings showing that a mucosal FlaB-tPspA fusion (flagellin fused with truncated PspA antigen of Streptococcus pneumoniae) vaccine-induced protective...

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Bibliographic Details
Main Authors: Tien Duc Nguyen, Hoang Duy Le, Giang Chau Dang, Hyun Seok Jung, Yoonjoo Choi, Koemchhoy Khim, Young Kim, Shee Eun Lee, Joon Haeng Rhee
Format: Article
Language:English
Published: Nature Portfolio 2025-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-58115-8
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