The underlying difference of metastatic and non-metastatic breast cancer cells in configuring type I collagen fibres to promote migration by cell mechanics

The underlying difference of metastatic and non-metastatic breast cancer cells in configuring type I collagen fibres to promote migration by cell mechanics

The progression of tumors is heavily influenced by mechanical properties of their microenvironment. In this work, we applied micropatterned models with varying distances and shapes to investigate the differences between metastatic MDA-MB-231 and non-metastatic MCF-7 breast cancer cells in reconfigur...

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Bibliographic Details
Main Authors: Mingxing Ouyang, Weihui Chen, Ting Zhou, Hongjie Liu, Lei Liu, Bing Bu, Linhong Deng
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Mechanobiology in Medicine
Subjects:
Cancer metastasis
Matrix remodeling
Mechanical communication
Integrin
Piezo
E-Cadherin
Online Access:http://www.sciencedirect.com/science/article/pii/S2949907025000014
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