Review: performance of jujube and its extracts in cancer: therapeutic, toxicity-reducing and potentiating effects
Cancer is one of the most serious public health challenges in the world. The number of new and fatal patients with cancer continues to increase every year, which poses a serious threat to human health. Although there are effective treatments such as radiotherapy and chemotherapy for cancers, they ar...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2025-01-01
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| Series: | Frontiers in Oncology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fonc.2025.1489974/full |
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| author | Boyun Gou Guoqing Chen Shicong Huang Na Ning Qian Gu Shuai Duan Yuhua Du Yi Nan Ling Yuan |
| author_facet | Boyun Gou Guoqing Chen Shicong Huang Na Ning Qian Gu Shuai Duan Yuhua Du Yi Nan Ling Yuan |
| author_sort | Boyun Gou |
| collection | DOAJ |
| description | Cancer is one of the most serious public health challenges in the world. The number of new and fatal patients with cancer continues to increase every year, which poses a serious threat to human health. Although there are effective treatments such as radiotherapy and chemotherapy for cancers, they are often accompanied by serious side effects. With the development of the pharmaceutical industry, there is a gradual desire to develop low-toxicity and effective anticancer drugs from traditional Chinese herbs. Due to its “homology of medicine and food,” jujube is one of the traditional Chinese herbs that is extensively used in China. In addition, jujube has received much attention around the world for its excellent pharmacological effects and food value. This article reviews the anticancer effects of a fruit, food, and drug, jujube, which have been shown in current studies, and analyzes its therapeutic mechanism, active ingredients, extraction and isolation methods, as well as its synergistic and attenuation performance in cancer. This will further promote the progress of natural medicine’s anti-cancer effect. |
| format | Article |
| id | doaj-art-c471e7de3eca4f2487f72e734d3df1bd |
| institution | Kabale University |
| issn | 2234-943X |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Oncology |
| spelling | doaj-art-c471e7de3eca4f2487f72e734d3df1bd2025-01-29T06:46:08ZengFrontiers Media S.A.Frontiers in Oncology2234-943X2025-01-011510.3389/fonc.2025.14899741489974Review: performance of jujube and its extracts in cancer: therapeutic, toxicity-reducing and potentiating effectsBoyun Gou0Guoqing Chen1Shicong Huang2Na Ning3Qian Gu4Shuai Duan5Yuhua Du6Yi Nan7Ling Yuan8College of Pharmacy, Ningxia Medical University, Yinchuan, Ningxia Hui Autonomous Region, ChinaCollege of Pharmacy, Ningxia Medical University, Yinchuan, Ningxia Hui Autonomous Region, ChinaCollege of Pharmacy, Ningxia Medical University, Yinchuan, Ningxia Hui Autonomous Region, ChinaCollege of Pharmacy, Ningxia Medical University, Yinchuan, Ningxia Hui Autonomous Region, ChinaCollege of Pharmacy, Ningxia Medical University, Yinchuan, Ningxia Hui Autonomous Region, ChinaCollege of Pharmacy, Ningxia Medical University, Yinchuan, Ningxia Hui Autonomous Region, ChinaCollege of Pharmacy, Ningxia Medical University, Yinchuan, Ningxia Hui Autonomous Region, ChinaKey Laboratory of Ningxia Ethnomedicine Modernization, Ministry of Education, Ningxia Medical University, Yinchuan, Ningxia Hui Autonomous Region, ChinaCollege of Pharmacy, Ningxia Medical University, Yinchuan, Ningxia Hui Autonomous Region, ChinaCancer is one of the most serious public health challenges in the world. The number of new and fatal patients with cancer continues to increase every year, which poses a serious threat to human health. Although there are effective treatments such as radiotherapy and chemotherapy for cancers, they are often accompanied by serious side effects. With the development of the pharmaceutical industry, there is a gradual desire to develop low-toxicity and effective anticancer drugs from traditional Chinese herbs. Due to its “homology of medicine and food,” jujube is one of the traditional Chinese herbs that is extensively used in China. In addition, jujube has received much attention around the world for its excellent pharmacological effects and food value. This article reviews the anticancer effects of a fruit, food, and drug, jujube, which have been shown in current studies, and analyzes its therapeutic mechanism, active ingredients, extraction and isolation methods, as well as its synergistic and attenuation performance in cancer. This will further promote the progress of natural medicine’s anti-cancer effect.https://www.frontiersin.org/articles/10.3389/fonc.2025.1489974/fulljujubehomology of medicine and foodanti-canceradverse reactionsextraction and separationattenuated toxicity and potentiating effects |
| spellingShingle | Boyun Gou Guoqing Chen Shicong Huang Na Ning Qian Gu Shuai Duan Yuhua Du Yi Nan Ling Yuan Review: performance of jujube and its extracts in cancer: therapeutic, toxicity-reducing and potentiating effects Frontiers in Oncology jujube homology of medicine and food anti-cancer adverse reactions extraction and separation attenuated toxicity and potentiating effects |
| title | Review: performance of jujube and its extracts in cancer: therapeutic, toxicity-reducing and potentiating effects |
| title_full | Review: performance of jujube and its extracts in cancer: therapeutic, toxicity-reducing and potentiating effects |
| title_fullStr | Review: performance of jujube and its extracts in cancer: therapeutic, toxicity-reducing and potentiating effects |
| title_full_unstemmed | Review: performance of jujube and its extracts in cancer: therapeutic, toxicity-reducing and potentiating effects |
| title_short | Review: performance of jujube and its extracts in cancer: therapeutic, toxicity-reducing and potentiating effects |
| title_sort | review performance of jujube and its extracts in cancer therapeutic toxicity reducing and potentiating effects |
| topic | jujube homology of medicine and food anti-cancer adverse reactions extraction and separation attenuated toxicity and potentiating effects |
| url | https://www.frontiersin.org/articles/10.3389/fonc.2025.1489974/full |
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