Advancing precision therapy for colorectal cancer: Developing clinical indications for multi-target kinase inhibitor BPR1J481 using patient-derived xenograft models

Advancing precision therapy for colorectal cancer: Developing clinical indications for multi-target kinase inhibitor BPR1J481 using patient-derived xenograft models

The large and rapid increase in the incidence and mortality of colorectal cancer (CRC) demonstrates the urgent need for new drugs with higher efficacy to treat CRC. However, the lack of applicable and reliable preclinical models significantly hinders the progress of drug development. Patient-derived...

Full description

Saved in:
Bibliographic Details
Main Authors: Ya-Chu Tang, Jing-Jim Ou, Shu-Ching Hsu, Chih-Hsiang Huang, Li-Mei Lin, Hsin-Huei Chang, Yi-Hsin Wang, Zih-Ting Huang, Manwu Sun, Ko-Jiunn Liu, Yi-Mei Hung, Chi-Yun Lai, Chuan Shih, Chiung-Tong Chen, Jang-Yang Chang, Hsing-Pang Hsieh, Weir-Torn Jiaang, Ching-Chuan Kuo
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Pharmacological Research
Subjects:
Colorectal cancer
patient-derived xenograft models
multi-target kinase inhibitor
SRC
Online Access:http://www.sciencedirect.com/science/article/pii/S1043661824005012
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

http://www.sciencedirect.com/science/article/pii/S1043661824005012

Similar Items