DNA-damage-associated protein co-expression network in cardiomyocytes informs on tolerance to genetic variation and disease

Summary: Cardiovascular disease (CVD) is associated with genetic variants and environmental factors. A consequence of multiple risk factors is DNA damage. To examine how DNA damage influences the cardiomyocyte proteome and its relationship to CVD risk, we treated human induced pluripotent stem cell...

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Bibliographic Details
Main Authors: Omar Darrel Johnson, Sayan Paul, José Angel Gutiérrez, William Kent Russell, Michelle Claire Ward
Format: Article
Language:English
Published: Elsevier 2025-05-01
Series:iScience
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Online Access:http://www.sciencedirect.com/science/article/pii/S2589004225007357
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