Post translational modification regulation of transcription factors governing pancreatic β-cell identity and functional mass

Dysfunction of the insulin-secreting β-cells is a key hallmark of Type 2 diabetes (T2D). In the natural history of the progression of T2D, factors such as genetics, early life exposures, lifestyle, and obesity dictate an individual’s susceptibility risk to disease. Obesity is associated with insulin...

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Bibliographic Details
Main Authors: Alicia Wong, Emilyn U. Alejandro
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-03-01
Series:Frontiers in Endocrinology
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Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2025.1562646/full
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