Exploring hypoxia driven subtypes of pulmonary arterial hypertension through transcriptomics single cell sequencing and machine learning

Exploring hypoxia driven subtypes of pulmonary arterial hypertension through transcriptomics single cell sequencing and machine learning

Abstract Pulmonary arterial hypertension (PAH) is a progressive cardiovascular disease characterized by elevated pulmonary arterial pressure, leading to right heart failure and death. Despite advancements in diagnosis and treatment, it remains incurable, and its mechanisms are poorly understood. Thi...

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Bibliographic Details
Main Authors: Jianghao Xiong, Jiali Chen, Jianjun Zhou, Chao Li, Jifeng Wu
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Scientific Reports
Subjects:
Pulmonary arterial hypertension
Hypoxia
Machine learning
Immune regulation and inflammation
Online Access:https://doi.org/10.1038/s41598-025-99025-5
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https://doi.org/10.1038/s41598-025-99025-5

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