Cyclooxygenase-2 inhibitors: promise or peril?

The discovery of two isoforms of the cyclooxygenase enzyme, COX-1 and COX-2, and the development of COX-2-specific inhibitors as anti-inflammatories and analgesics have offered great promise that the therapeutic benefits of NSAIDs could be optimized through inhibition of COX-2, while minimizing thei...

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Bibliographic Details
Main Authors: Laurel J. Mengle-Gaw, Benjamin D. Schwartz
Format: Article
Language:English
Published: Wiley 2002-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1080/09629350290000041
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