Is a single lethal electric field threshold sufficient to characterize the lesion size in computational modeling of cardiac pulsed-field ablation?

Is a single lethal electric field threshold sufficient to characterize the lesion size in computational modeling of cardiac pulsed-field ablation?

Background: Pulsed-field ablation (PFA) is a novel cardiac ablation technology based on irreversible electroporation (IRE). PFA computational models rely on identification of a lethal electric field threshold to predict the IRE area. However, the predicted lesion anisotropy ratios (width over depth)...

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Bibliographic Details
Main Authors: Argyrios Petras, PhD, Gerard Amoros Figueras, PhD, Zoraida Moreno Weidmann, MD, Tomás García-Sánchez, PhD, David Viladés Medel, MD, PhD, Antoni Ivorra, PhD, Jose M. Guerra, MD, PhD, Luca Gerardo-Giorda, PhD
Format: Article
Language:English
Published: Elsevier 2025-05-01
Series:Heart Rhythm O2
Subjects:
Cardiac ablation
Computer simulations
Pulsed field ablation
Electric field threshold
Mathematical modeling
Online Access:http://www.sciencedirect.com/science/article/pii/S2666501825000790
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