Osteoclasts and CD8 T Cells Form a Negative Feedback Loop That Contributes to Homeostasis of Both the Skeletal and Immune Systems
There are a number of dynamic regulatory loops that maintain homeostasis of the immune and skeletal systems. In this review, we highlight a number of these regulatory interactions that contribute to maintaining homeostasis. In addition, we review data on a negative regulatory feedback loop between o...
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| Format: | Article |
| Language: | English |
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Wiley
2013-01-01
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| Series: | Clinical and Developmental Immunology |
| Online Access: | http://dx.doi.org/10.1155/2013/429373 |
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| _version_ | 1832555880052162560 |
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| author | Zachary S. Buchwald Rajeev Aurora |
| author_facet | Zachary S. Buchwald Rajeev Aurora |
| author_sort | Zachary S. Buchwald |
| collection | DOAJ |
| description | There are a number of dynamic regulatory loops that maintain homeostasis of the immune and skeletal systems. In this review, we highlight a number of these regulatory interactions that contribute to maintaining homeostasis. In addition, we review data on a negative regulatory feedback loop between osteoclasts and CD8 T cells that contributes to homeostasis of both the skeletal and immune systems. |
| format | Article |
| id | doaj-art-c2ddc80fb37d47fa97ddaae15a7f714d |
| institution | Kabale University |
| issn | 1740-2522 1740-2530 |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Clinical and Developmental Immunology |
| spelling | doaj-art-c2ddc80fb37d47fa97ddaae15a7f714d2025-02-03T05:47:05ZengWileyClinical and Developmental Immunology1740-25221740-25302013-01-01201310.1155/2013/429373429373Osteoclasts and CD8 T Cells Form a Negative Feedback Loop That Contributes to Homeostasis of Both the Skeletal and Immune SystemsZachary S. Buchwald0Rajeev Aurora1Department of Molecular Microbiology and Immunology, Saint Louis University School of Medicine, 1100 S. Grand Boulevond DRC 605, St. Louis, MO 63104, USADepartment of Molecular Microbiology and Immunology, Saint Louis University School of Medicine, 1100 S. Grand Boulevond DRC 605, St. Louis, MO 63104, USAThere are a number of dynamic regulatory loops that maintain homeostasis of the immune and skeletal systems. In this review, we highlight a number of these regulatory interactions that contribute to maintaining homeostasis. In addition, we review data on a negative regulatory feedback loop between osteoclasts and CD8 T cells that contributes to homeostasis of both the skeletal and immune systems.http://dx.doi.org/10.1155/2013/429373 |
| spellingShingle | Zachary S. Buchwald Rajeev Aurora Osteoclasts and CD8 T Cells Form a Negative Feedback Loop That Contributes to Homeostasis of Both the Skeletal and Immune Systems Clinical and Developmental Immunology |
| title | Osteoclasts and CD8 T Cells Form a Negative Feedback Loop That Contributes to Homeostasis of Both the Skeletal and Immune Systems |
| title_full | Osteoclasts and CD8 T Cells Form a Negative Feedback Loop That Contributes to Homeostasis of Both the Skeletal and Immune Systems |
| title_fullStr | Osteoclasts and CD8 T Cells Form a Negative Feedback Loop That Contributes to Homeostasis of Both the Skeletal and Immune Systems |
| title_full_unstemmed | Osteoclasts and CD8 T Cells Form a Negative Feedback Loop That Contributes to Homeostasis of Both the Skeletal and Immune Systems |
| title_short | Osteoclasts and CD8 T Cells Form a Negative Feedback Loop That Contributes to Homeostasis of Both the Skeletal and Immune Systems |
| title_sort | osteoclasts and cd8 t cells form a negative feedback loop that contributes to homeostasis of both the skeletal and immune systems |
| url | http://dx.doi.org/10.1155/2013/429373 |
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